1. Honest Paws Calm CBD Oil Tincture for Dogs

Honest Paws Calm CBD Oil Tincture for Dogs is a full-spectrum CBD oil for dogs formulated to promote relaxation and reduce anxiety, while combining the calming properties of CBD and chamomile. It is made from organically grown hemp plants and features the National Animal Supplement Council (NASC) quality seal.

Ingredients: Organic MCT Oil, Organic US Grown Hemp Oil, Organic Chamomile

Best for: The Honest Paws Calm CBD Oil Tincture is the overall best CBD product with full-spectrum hemp extract for small to large dogs with situational or habitual anxiety.

Potency Options: 125 mg, 250 mg, 500 mg, 1000 mg

The Honest Paws Calm CBD Oil Tincture has a rating of 4.5/5 stars from over 1,300 reviews, with 95% of users saying it helps manage stress. Plus, it is vet-recommended, third-party lab tested, and fast-acting.

Pet parents are more than happy with Honest Paws’ calming CBD oil for dogs – as many as 95% of customers say the Calm Oil helps manage occasional stress in their furry friends.

2. Penelope’s Bloom CBD Soft Chews for Stress + Anxiety

Penelope’s Bloom CBD Soft Chews for Stress + Anxiety are soft chews formulated to help alleviate stress and anxiety in medium to large-sized dogs, containing up to 600 mg of full-spectrum CBD oil along with natural calming agents.

Ingredients: Full-Spectrum CBD Oil, MCT Oil, Chamomile, Valerian Root, L-Tryptophan, GABA, Organic Sweet Potato, Organic Brown Rice Flour, Molasses, Natural Flavorings

Best for: The Penelope’s Bloom CBD Soft Chews for Stress + Anxiety are the best CBD and strongest contender for dogs needing both CBD and herbal support to ease anxiety.

Potency Options: 300 mg (10mg/chew; 30 chews/bag), 600 mg (20 mg/chew; 30 chews/bag)

Featuring full-spectrum hemp extract, the CBD chews are non-GMO, vegan, and peanut butter flavored for easy use. They are made in the US without artificial flavors, preservatives, or fillers.

Penelope’s Bloom is a trusted brand that offers a range of dog CBD oil formulas to support everyday well-being. Pet parents highly recommend its line of products.

3. ElleVet Calm & Comfort Chews

ElleVet Calm + Comfort Chews are delicious CBD chews designed to provide rapid support for dogs during stressful situations such as fireworks, travel, or vet visits. They are made with the brand’s proprietary full-spectrum CBD oil for maximum pet wellness.

Ingredients: Hemp Oil (CBD + CBDA), Brewer’s Yeast, Coconut Glycerin, DigestaWell PET (flavor), Dry Molasses, Guar Gum, Lecithin, Organic Sesame Seed Oil, Palteva (flavor), Peanut Butter, Pork Flavoring, Potato Starch, Rice Bran, Sorbic Acid, Sugar, Sweet Potato, Tapioca Starch

Best for: The ElleVet Calm + Comfort Chews are the best CBD option for dogs with situational anxiety related to vet visits, grooming, thunderstorms, car travel, separation events, and kennel stays.

Potency Options: 45 mg/chew (4 soft chews/pack; 38 soft chews/pack)

The chews are pork-flavored and easy to use for dogs with delicate palates. The CBD chews have a soft texture, which makes them suitable for dogs of all ages, including puppies and senior dogs.

ElleVet is a top-tier CBD brand with a broad range of products. Each ElleVet product formula is backed by science. The Calm & Comfort Chews are great for reducing stress, as reported by many pet parents.

4. NuLeaf Naturals CBD Calming Chews for Dogs

NuLeaf Naturals CBD Calming Chews for Dogs are treats with hemp-sourced, full-spectrum CBD oil designed to promote calmness in dogs. Each chew contains 6mg of cannabinoids (4mg CBD and 2mg CBN) and is formulated with natural ingredients to support relaxation.

Ingredients: Chamomile, L-Theanine, CBD, CBN, Apple Sauce, Buffered, Distilled White Vinegar, Cinnamon, Citric Acid, Coconut Glycerin, Coconut Oil, Molasses, Olive Oil, Organic Brown Rice Flour, Organic Oat Flour, Peanut Butter, Rosemary Extract, Sunflower Lecithin, Sunflower Oil, Sweet Potato, Water

Best for: The NuLeaf Naturals CBD Calming Chews for Dogs are the best CBD product for dogs with mild to moderate anxiety.

Potency Options: 180 mg (6 mg/chew; 30 chews/bag)

The NuLeaf Naturals are crafted under rigorous quality standards. They contain USDA-certified organic hempseed carrier oil and are free from pesticides, heavy metals, and mycotoxins.

NuLeaf Naturals is a respected CBD brand that makes products for both humans and pets, including CBD oil, CBD treats, CBD topicals, CBD edibles, CBD drinks, and CBD capsules.

5. Charlotte’s Web Calming Chews for Dogs

Charlotte’s Web Calming Chews for Dogs are soft chews formulated to promote relaxation in dogs, combining full-spectrum hemp extract with natural calming botanicals. They help manage stress from traveling, hospitalization, and loud noises, while maintaining a normal emotional balance.

Ingredients: Full-Spectrum Hemp Extract, Valerian Root, Passionflower Extract, Chamomile, Brewers Dried Yeast, Chicken Liver Hydrolysate, Coconut Glycerin, MCT Oil, Natural Flavor, Natural Tocopherols, Potato Flour, Potato Starch, Salt, Sunflower Lecithin, Sunflower Seed Oil, Water

Best for: Charlotte’s Web Calming Chews for Dogs are the best CBD option for dogs experiencing chronic stress or daytime/nighttime anxiety, as they promote a calming effect without heavy sedation.

Potency Options: 75 mg (2.5 mg/chew; 30 chews/bag), 150mg (2.5mg/chew; 60 chews/bag)

Featuring a delicious chicken flavor, the CBD chews are easy to use for furry friends with picky appetites. The hemp is US-grown, and the product has the NASC quality seal.

Pet owners rate Charlotte’s Web as a reliable CBD brand, best known for using high-quality CBD oil in its line of pet hemp products.

How Can CBD Oil Help Dogs with Anxiety?

CBD oil can help dogs with anxiety by interacting with the endocannabinoid system (ECS), a regulatory system present in all mammals that influences mood, emotions, and stress responses. CBD is believed to mirror the effects of serotonin and influence brain receptors associated with fear and anxiety, making it a popular natural option for anxious pets.

According to a 2023 study, a single dose of CBD can significantly reduce serum cortisol levels in dogs experiencing stress from separation or car travel. Dogs treated with CBD were rated as significantly less “stressed,” “sad,” “tense,” and “uncomfortable” compared to those given a placebo.

Before choosing a CBD product, it’s worth understanding whether your dog is dealing with situational or chronic anxiety, this affects how and when you’d use CBD.

How to Treat Your Dog’s Anxiety with CBD Oil

To get the most out of calming CBD oil for dogs, follow these steps:

Choose the right product type. Calming CBD for dogs is available as oils, chews, capsules, and powders. Choose whichever form is easiest to administer consistently.

Find the right dosage. The recommended oral dose is between 1 and 5 mg per 10 pounds of body weight. Start at the lower end and increase gradually until your dog is calm and relaxed.

Set a dosing schedule. Dogs with chronic anxiety benefit from daily CBD use. For situational anxiety, administer CBD 45 minutes to 1 hour before an anticipated stressful event, such as fireworks, travel, or a vet visit.

Combine with other treatments if needed. Calming CBD is safe to use alongside traditional anti-anxiety medications. Your veterinarian can help determine the best combined management plan for your pet.

How Much CBD Oil Can You Give to Your Dog?

You can give your dog between 1 and 5 mg per 10 pounds of body weight per day. Finding the right dose takes some trial and error: start low and adjust based on your dog’s response. Each dog can differ to how they respond to CBD products, so personalized dosing is key.

Accidental overdosing with hemp-sourced, pet-formulated CBD is not a significant concern. In the worst-case scenario, a dog may be drowsy and sleep through the effects. To be sure to administer the right CBD amount, you can use Totalvet’s dosage calculator and you can always consult with a veterinarian.

How to Choose the Right CBD Oil for Your Dog

Extract type: Full-spectrum CBD products are often preferred, as they include the natural range of hemp compounds that may enhance calming effects. Full-spectrum oil also allows for precise, drop-by-drop dosing.

Supplement format: Oils are fast-acting but can be harder to administer due to their earthy taste. Chews are more palatable and convenient, especially for travel or picky eaters.

Hemp sourcing: Always confirm the product is sourced from hemp, not marijuana. THC concentrations below 0.3% are safe for dogs.

Certificate of Analysis (COA): Always look for a third-party lab COA confirming the product is free from pesticides, heavy metals, and unsafe THC levels.

Formula ingredients: Many pet parents find that CBD products formulated with additional calming agents like chamomile and L-theanine provide stronger results for naturally anxious or reactive dogs.

Potency: Match the CBD concentration to your dog’s size — lower potency for small breeds, higher potency for large dogs — to simplify dosing calculations.

Flavor: CBD is naturally bitter. Look for dog-friendly flavors like chicken, beef, or bacon, especially for picky eaters.

Brand reputation: Buy from transparent brands that publish their ingredient sourcing and manufacturing practices, and read customer reviews before purchasing.

Does CBD Oil Have Side Effects for Dogs?

Yes, CBD oil can have side effects, though they are generally mild. These include dry mouth, low blood pressure, lethargy, and digestive upset such as vomiting or diarrhea, although the latter is typically caused by the carrier oil rather than the CBD itself. Some clinical studies also suggest that CBD may affect liver enzyme production in certain pets.

Side effects can be minimized by using high-quality products and introducing CBD gradually. They generally resolve once the dose is adjusted and the dog’s body adapts. Always consult a veterinarian before starting CBD, particularly if your dog is on other medications.

Is Continued CBD Treatment Necessary for Dogs with Anxiety?

Yes, consistency matters. CBD works best when used regularly, as cannabinoids need time to build up in the dog’s system — it can take several weeks before you notice a meaningful improvement in an anxious dog’s demeanor.

For situational anxiety, occasional dosing approximately 45 minutes to 1 hour before a stressful event is about to happen can be effective. For dogs with habitual or chronic anxiety, daily use tends to produce more stable, long-term results.

CBD sourced from hemp and formulated for pets is non-addictive and safe for long-term use in healthy dogs.